lupus induction test - definition. What is lupus induction test
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%ما هو (من)٪ 1 - تعريف

TYPE OF IMMUNOGLOBULIN
Lupus coagulation inhibitor; Lupus Anticoagulant Test; Lupus anticoagulant, familial; Familial lupus anticoagulant

Lupus anticoagulant         
Lupus anticoagulant is an immunoglobulin that binds to phospholipids and proteins associated with the cell membrane. Its name is a partial misnomer, as it is actually a prothrombotic antibody in vivo.
lupus erythematosus         
HUMAN DISEASE
Lupus Erythematosus; Cutaneous lupus erythematosus; Subacute lupus erythematosus; Pterygium formation in lupus erythematosus; Lupus mutilans; Cazenave's disease; Lupus erythematodes tumidus; Chronic discoid lupus erythematosus; Non-tuberculous lupus; Lupus erythematodes verrucosus; Lupus erythematosus, cutaneous, NEC; Lupus erythematosus(LE)-like syndrome due to drug; Greenwald's Law of Lupus; Greenwald Law of Lupus; Bullous lupus erythematosus
[??r??i:m?'t??s?s]
¦ noun an inflammatory disease causing scaly red patches on the skin.
Origin
from lupus + mod. L. erythematosus, from Gk eruthema 'reddening'.
SLE         
  • epidermal]] cells (antinuclear antibodies are present).
  • Clearance deficiency
  • Germinal centres in a person with SLE and controls (schematic). Red: CD68 in tingible body macrophages; black: TUNEL positive apoptotic cells. 1) Healthy donors with florid germinal centres show giant tingible body macrophages (TBM) containing ingested apoptotic cells and no uningested apoptotic cells outside the TBM. 2) People with follicular lymphoma show small tingible body macrophages (TBM) containing few ingested apoptotic cells however, there are no uningested apoptotic cells outside the TBM. 3) Some with SLE (1) show a lack of TBM and many uningested apoptotic cells decorating the surfaces of spindle-shaped cells, presumably follicular dendritic cells (SLE 1). 4) Some people with SLE show TBM containing few ingested apoptotic cells and many uningested apoptotic cells outside the TBM (SLE 2). However, about 50 % of people with SLE show rather normal germinal centre.
  • date=2009-12-20 }} Last Editorial Review: 2009-01-30</ref>
INFLAMMATION OF CONNECTIVE TISSUE MARKED BY SKIN RASHES, JOINT PAIN AND SWELLING, INFLAMMATION OF THE KIDNEYS AND INFLAMMATION OF THE TISSUE SURROUNDING THE HEART.
Systemic Lupus Erythematosus; Lupus erythematodes; Systemic lupus erythamatosus; Lupus erythematosus, systemic; Lupus erythematosus, discoid; Lupus erythematosus, cutaneous; Systemic lupus erythematosis; Lupus disease; Osler-Libman-Sacks syndrome; Childhood systemic lupus erythematosus; Erythematosus; Lupus (S LE); Systemic lupus erythmatosis; Systemic lupus; Lupus erythematous; Lupus and the brain; Lupus treatment; Systemic lupus erythematosus; Angiolupoid; Lupoid syndrome; Systemic Lupus Erythematosus (SLE); Systemic lupus erythematosus (SLE); Systemic lupus erythemaosus; SLE; Osler–Libman–Sacks syndrome; Disseminated lupus erythematosus
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ويكيبيديا

Lupus anticoagulant

Lupus anticoagulant is an immunoglobulin that binds to phospholipids and proteins associated with the cell membrane. Its name is a partial misnomer, as it is actually a prothrombotic antibody in vivo. Lupus anticoagulant in living systems causes a decrease in clotting time. The name derives from their properties in vitro, as these antibodies increase coagulation times in laboratory tests such as the activated partial thromboplastin time (aPTT). Investigators speculate that the antibodies interfere with phospholipids used to induce in vitro coagulation. In vivo, the antibodies are thought to interact with platelet membrane phospholipids, increasing adhesion and aggregation of platelets, which accounts for the in vivo prothrombotic characteristics.

The condition was first described by hematologist C. Lockard Conley in 1952.